The speculation that creatine causes hair loss was most likely a response to the findings of a 2009 study by van der Merwe et al, which noted an increase in both dihydrotestosterone (DHT) and the DHT:Testosterone ratio in college-aged Rugby players after a three-week intervention of creatine supplementation vs placebo.. Yes, creatine can cause hair loss. However, the process is indirect. Creatine supplements cause an increase in DHT levels, which alters the enzyme that converts testosterone to DHT. Thus, causing hair loss. Ideally, hair follicles' growth follows a cycle of growth, the resting phase, and the falling of hair follicles.

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However, the truth is the two are not related. According to a literature review published in the Journal of the International Society of Sports Nutrition (JISSN), creatine does not cause hair loss. That's because it has no effect on the levels of testosterone or dihydrotestosterone in the body.. Creatine and hair help to improve the dry feel of hair when used before bleaching and permanent waving the hair. In a study applying creatine on hair, creatine was able to help smooth the surface of the hair when used 5 times, allowing creatine to soak into hair for 5 minutes and then either rinsed or left in the hair.